Thrive Brain & Mind is a full-service psychiatric practice in Powell, Ohio, serving patients across the greater Columbus area. What sets us apart is our combination of traditional psychiatry with interventional treatments — Spravato (esketamine), TMS, medicinal marijuana, and ketamine therapy — all under the care of Dr John Aziz, a quadruple board-certified psychiatrist with over 30 years of clinical experience.
We have two locations in Ohio — our primary clinic in Powell and a second location in Logan. We proudly serve patients throughout the greater Columbus area, including Dublin, Westerville, Lewis Center, Delaware, Upper Arlington, Hilliard, and beyond. Many patients travel to us from across Ohio specifically for our Spravato (esketamine) and TMS programs. We offer telehealth (virtual consultation) statewide.
We provide psychiatric care for children, adolescents, and adults of all ages. Every treatment plan is individualized to reflect the unique needs, history, and goals of each patient — regardless of age.
We offer comprehensive psychiatric services including evaluation, diagnosis, medication management, and ongoing psychiatric care. We also specialize in interventional psychiatry — Spravato (esketamine), Transcranial Magnetic Stimulation (TMS), and ketamine therapy — for patients who haven’t found adequate relief through traditional approaches. Additionally, we offer Medical Marijuana certifications for qualifying Ohio patients.
Spravato is an FDA-approved nasal spray containing esketamine — a compound derived from ketamine — specifically approved for treatment-resistant depression (TRD) in adults who have not responded to at least two oral antidepressants. It is also approved for major depressive disorder with acute suicidal ideation. Spravato is administered in our clinic under medical supervision and requires a 2-hour monitoring period after each session. It is not a take-home medication.
No — though they are related. Spravato contains esketamine, which is the S-enantiomer of ketamine, delivered as a nasal spray. It is FDA-approved specifically for treatment-resistant depression and administered in a REMS-certified clinical setting like ours. Ketamine (racemic ketamine) is used off- label and is typically delivered by infusion. Both work through the NMDA receptor pathway, but they differ in formulation, delivery method, FDA approval status, and insurance coverage.
Yes — because Spravato is FDA-approved, it is covered by most commercial insurance plans and Medicare for patients who meet clinical criteria. Coverage typically requires documentation of treatment-resistant depression and prior treatment failures. Our team will work with your insurance to verify benefits before you begin treatment.
You arrive at our Powell clinic, self-administer the nasal spray under clinical supervision, and then rest in our monitoring area for approximately two hours. You may experience temporary dissociation, dizziness, or nausea during or shortly after administration — these are expected effects and resolve before you leave. You cannot drive the day of your treatment, so you will need to arrange transportation.
The standard induction phase is twice-weekly sessions for four weeks. After that, sessions taper to once weekly, then once every one to two weeks for maintenance. Response varies by patient — some notice improvement within the first few weeks. Your treatment plan will be monitored and adjusted based on your response.
No. You cannot drive or operate heavy machinery on the day of your Spravato treatment due to its temporary effects on perception and reaction time. You must arrange a ride home. This is a requirement of the FDA’s REMS program, not a practice-specific policy.
Transcranial Magnetic Stimulation (TMS) is a non-invasive, FDA-cleared treatment for depression that uses focused magnetic pulses to stimulate specific areas of the brain involved in mood regulation. Sessions are conducted in our office, require no sedation or anesthesia, and patients can return to normal activities immediately afterward. TMS does not involve medication, needles, or surgery.
TMS is typically recommended for adults with treatment-resistant depression — meaning depression that has not responded to one or more antidepressant medications. It is also an option for patients who prefer to avoid medication side effects or cannot tolerate antidepressants. Dr. Aziz will evaluate your history to determine whether TMS is appropriate for you.
Yes — TMS is FDA-cleared for treatment-resistant depression and is covered by most major commercial insurance plans and Medicare when clinical criteria are met. Coverage generally requires documented prior treatment failures. We handle insurance verification as part of the intake process.
A standard TMS course typically involves sessions five days a week for four to six weeks. Each session lasts approximately 20 to 40 minutes. You can drive yourself to and from appointments and continue your normal daily routine throughout your treatment.
Most patients describe a tapping or clicking sensation on the scalp during treatment. Some experience mild headaches in the first few sessions, which typically resolve on their own. TMS is well- tolerated and does not require any sedation. There is no recovery period.
TMS and ECT both target brain activity, but they are very different in practice. ECT uses electrical currents and requires general anesthesia; it is typically reserved for the most severe cases of psychiatric illness. TMS is non-invasive, requires no anesthesia, causes no seizures, and has a significantly milder side effect profile. Most patients continue working and driving throughout their TMS treatment course.
We offer ketamine therapy as an off-label treatment option for severe, treatment-resistant depression, bipolar depression, and PTSD in appropriate patients. Ketamine works through a different mechanism than traditional antidepressants — targeting NMDA receptors — and can provide rapid symptom relief for some patients who have not responded to other treatments.
Ketamine itself is not FDA-approved for depression — it is used off-label, which means it is a legal, physician-supervised treatment applied outside its original FDA approval (which was an anesthetic). This is common and accepted in medicine. Spravato (esketamine), a related compound, is FDA- approved for treatment-resistant depression and administered in our clinic as well. We will explain the distinction clearly during your consultation so you can make an informed decision.
Spravato is a specific, FDA-approved form of esketamine delivered as a nasal spray under REMS protocols. Ketamine refers to the racemic compound used off-label and is typically administered differently. Both share a similar mechanism of action. Key differences include FDA approval status, insurance coverage (Spravato is typically covered; ketamine is often self-pay), and administration method. Your provider will discuss which option, if either, is appropriate for your situation.
Yes. Dr. Aziz is certified to recommend Medical Marijuana for qualifying Ohio patients. Ohio’s Medical Marijuana program covers a range of qualifying conditions including PTSD, chronic pain, anxiety, and others as defined by state law. Medical Marijuana is not FDA-approved as a treatment, and our recommendation does not replace a standard treatment plan — it is offered as one option within a broader, individualized care approach.
Ohio’s qualifying conditions include, but are not limited to: PTSD, chronic pain, cancer, epilepsy/seizure disorders, Crohn’s disease, glaucoma, hepatitis C, HIV/AIDS, inflammatory bowel disease, multiple sclerosis, Parkinson’s disease, sickle cell anemia, spinal cord disease or injury, Tourette syndrome, traumatic brain injury, and terminal illness. Dr. Aziz will review your history to determine whether you qualify under Ohio law.
Call our Powell office to schedule an initial evaluation with Dr. Aziz or one of our providers. During your first visit, we will conduct a thorough psychiatric evaluation, review your history, discuss your goals, and develop a personalized treatment plan. No referral is required, though we are happy to coordinate with your primary care provider or referring specialist.
Not necessarily. Your physician is welcome to send a referral, but you can also self-refer.
No, as long as your insurance is one of the different insurance plans listed here.
Please bring a photo ID, your insurance card, a list of current medications (including dosages), and a list of any psychiatric medications you have tried in the past. If you have records from prior psychiatric providers, those are helpful but not required. Arriving a few minutes early to complete intake paperwork is appreciated.
Yes. We offer telehealth appointments for established patients and select new patient evaluations. Virtual visits offer the same quality of care with added convenience — particularly useful for patients managing busy schedules or travelling from across Central Ohio. Contact our office to confirm whether a telehealth visit is appropriate for your specific needs.
Please get in touch with us directly. We recommend calling rather than relying solely on online forms for the fastest response.
Powell Office:
3785 Attucks Dr
Powell, OH 43065
Phone 614-588-8177
Fax 614-522-6604
Mon-Fri 8:30 am – 6:00 pm
Saturday 9:00 am – 4:00 pm
Logan Office:
61 N. Orchard St.
Logan, OH 43138
Mon & Thu 10 am –4 pm by appointment only
Yes. For Spravato and TMS, we accept a wide range of commercial insurance plans, Medicaid managed care plans, and Medicare. Coverage for specific services — particularly Spravato and TMS — depends on your plan and whether clinical criteria are met. We strongly recommend calling our office before your first appointment so we can verify your specific benefits and discuss any out-of- pocket costs. Our office can help you navigate insurance coverage and other benefits.
We offer self-pay options and can discuss costs openly during your consultation. We offer self-pay options and can discuss costs openly during your consultation. For Spravato, the manufacturer (Janssen) offers affordability programs to help reduce costs. For patients with commercial insurance, their savings program can help cover out-of-pocket co-pays. For patients who are uninsured or underinsured, separate patient assistance programs may provide the medication at no cost to those who qualify. Our team will help you navigate these options before you commit to any treatment plan. Please note that while intravenous or intramuscular ketamine injections are also used to treat depression, this is an off-label use that is typically not covered by insurance and is managed under a self-pay structure.
If you are in crisis or experiencing a psychiatric emergency, call 911 or go to your nearest emergency room immediately. You can also call or text 988 — the Suicide & Crisis Lifeline — for immediate support. For urgent concerns during office hours, call our office and we will assist you in getting the appropriate level of care.
Yes, our office is fully accessible. If you have specific accommodation needs, please let us know when scheduling, and we will make sure your visit is comfortable.
